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Table 3 Differences between survival rates at 1, 3, 5 and 10 years, in patients with pemphigus vulgaris

From: Prediction of survival for patients with pemphigus vulgaris and pemphigus foliaceus: a retrospective cohort study

Characteristic Survival rate (%) 3 5 10 p-value
Follow up (years) 1
Age of onset ≥ 65 years 72.2% 67.4% 48.4% 41.5% < 0.001
Age of onset < 65 years 97.3% 97.3% 91.4% 91.4%  
Survival difference (%) 25.1% 29.9% 43.0% 49.9%  
Gender (M) 88.0% 88.0% 83.6% 83.6% 0.611
Gender (F) 93.3% 91.3% 78.7% 75.1%  
Survival difference (%) 5.3% 3.3% 4.9% 8.5%  
Ethnicity (Romanian) 90.6% 89.3% 81.1% 79.0% 0.816
Ethnicity (Roma) 100.0% 100.0% 75.0% 75.0%  
Survival difference (%) 9.4% 10.7% 6.1% 4.0%  
Alcohol consumption (Yes) 83.3% 83.3% 83.3% 83.3% 0.997
Alcohol consumption (No) 92.8% 91.4% 80.1% 77.5%  
Survival difference (%) 9.5% 8.1% 3.2% 5.8%  
Smoking (Yes) 92.1% 92.1% 92.1% 92.1% 0.299
Smoking (No) 90.9% 89.4% 78.1% 75.6%  
Survival difference (%) 1.2% 2.7% 14.0% 16.5%  
Subtype of PV      
Mucocutaneous 90.8% 89.2% 76.8% 76.8% 0.692
Cutaneous 92.3% 92.3% 92.3% 92.3%  
Mucous 92.9% 92.9% 92.9% 79.6%  
High blood pressure (Yes) 88.5% 83.6% 77.2 % 70.7 % 0.303
High blood pressure (No) 92.0% 92.0% 81.8% 81.8%  
Survival difference (%) 3.5% 8.4% 4.6% 11.1%  
Coronary heart disease (Yes) 70.7% 70.7% 58.9% 44.2% 0.003
Coronary heart disease (No) 93.4% 92.0% 83.1% 83.1%  
Survival difference (%) 22.7% 21.3% 24.2% 38.9%  
Heart failure (Yes) NA 100.0% 100.0% 0.0% 0.697
Heart failure (No) 90.8% 89.5% 79.9% 79.9%  
Survival difference (%) NA 10.5% 20.1% 79.9%  
Cardiac arrhythmia (Yes) 53.3% 53.3% 53.3% 26.7% 0.001
Cardiac arrhythmia (No) 92.8% 91.5% 81.7% 81.7%  
Survival difference (%) 39.5% 38.2% 28.4% 55.0%  
Diabetes mellitus (Yes) 87.5% 87.5% 65.6% 65.6%  
Diabetes mellitus (No) 91.5% 90.2% 81.8% 79.6%  
Survival difference (%) 4.0% 2.7% 16.2% 14.0% 0.438
Stroke (Yes) 80.0% 80.0% 80.0% 80.0% 0.749
Stroke (No) 91.7% 90.5% 80.6% 78.4%  
Survival difference (%) 11.7% 10.5% 0.6% 1.6%  
Depression (Yes) 80.0% 80.0% 80.0 % 80.0% 0.629
Depression (No) 91.7% 90.4% 80.8% 78.7%  
Survival difference (%) 11.7% 10.4% 0.8% 1.3%  
Dental problems (Yes) 90.5% 88.0% 84.8% 84.8% 0.508
Dental problems (No) 91.9% 91.9% 77.2% 73.6%  
Survival difference (%) 1.4% 3.9% 7.6% 11.2%  
ESR ≥ 30 mm/hour 84.6% 80.4% 66.4% 60.9% 0.039
ESR < 30 mm/hour  93.6% 93.6% 88.9% 88.9%  
Survival difference (%) 9.0% 13.2% 22.5% 28.0%  
Steroids ≥ 1 mg/kg/day 93.3% 93.3% 84.9% 84.8% 0.726
Steroids < 1 mg/kg/day 93.6% 92.0% 81.0% 78.1%  
Survival difference (%) 0.3% 1.3% 3.9% 6.7%  
Anti-Dsg1 autoAbs ≥ 100 U/mL 84.2 % 81.3% 68.8% 68.8% 0.039
Anti-Dsg1 autoAbs < 100 U/mL 96.1 % 96.1% 88.3% 84.9%  
Survival difference (%) 11.9 % 14.8% 19.5 % 16.1%  
Anti-Dsg3 auto Abs ≥ 100 U/mL 91.3% 89.5% 80.4% 80.4% 0.506
Anti-Dsg3 auto Abs < 100 U/mL 89.3% 89.3% 78.8% 71.6%  
Survival difference (%) 2.0% 0.2% 1.6% 8.8%