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Table 3 Severity of FMF in MEFV mutation-negative patients

From: Familial Mediterranean fever without MEFV mutations: a case–control study

Severity score

Mutation-negative (N = 47)

Heterogeneous controls (N = 60)

P value *

M694V homozygous (N = 57)

P value #

Mild

27 (57.4%)

23 (38.3%)

 

1 (1.8%)

 

Moderate

9 (19%)

6 (10%)

0.0049

5 (8.8%)

0.0001

Severe

11 (23.4%)

31 (51.7%)

 

51(89.4%)

 
  1. *Mutation-negative vs. genetically heterogeneous controls.
  2. #Mutation-negative vs. p.M694V homozygous patients.
  3. Bold values=statistically significant.
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172