Table 2 Differential diagnosis and underlying molecular basis
From: Olmsted syndrome: clinical, molecular and therapeutic aspects
Disease | Gene | Mode of inheritance |
|---|---|---|
Vohwinkel syndrome | GJB2, LOR | Autosomal dominant |
Mal de Meleda | SLURP1 | Autosomal recessive |
Papillon-Lefèvre syndrome | CTSC | Autosomal recessive |
Clouston syndrome | GJB6 | Autosomal dominant |
Pachyonychia congenita | KRT6A, KRT6B, KRT16 and KRT17 | Autosomal dominant |
Tyrosinemia type II | TAT | Autosomal recessive |
Haim-Munk syndrome | CTSC | Autosomal recessive |
Acrodermatitis enteropathica | SLC39A4 | Autosomal recessive |