Figure 3From: Natural disease history and characterisation of SUMF1 molecular defects in ten unrelated patients with multiple sulfatase deficiency Structural modifications of FGE due to mutations identified in MSD patients. Details of the conformation of wt (left panel) and mutant (right panel) FGE are shown for three missense mutations: p.R343S (A); p.A298E (B) and p.N259S (C).Back to article page