Elevated risk of thrombophilia in agenesis of the vena cava as a factor for deep vein thrombosis

Table 4 Prevalence of hereditary coagulation defects in patients with aivc and in patients with noaivc

Characteristic	Prevalence among patients with NoAIVC (n = 168)	Prevalence among patients with AIVC (n = 165)*	P value ^† (NoAIVC vs. AIVC)
Characteristic	Percent		P value ^† (NoAIVC vs. AIVC)
Gender (male)	46.4	73.9	<0.0001
Factor V Leiden	4.8	16.4	0.001
MTHFR gene mutation	3.6	12.7	0.005
Homocysteinemia	3.0	12.1	<0.0001
Prothrombin gene mutation	1.2	5.5	0.171
Lupus anticoagulant	0.6	3.6	0.053

AIVC inferior vena cava agenesia. NoAIVC iliofemoral DVT with involvement of inferior vena cava without AIVC.
*AIVC in this paper and in literature (n = 165).
^†P values are for the univariate comparison between patients with NoAIVC and those with AIVC.

ISSN: 1750-1172