Table 4 Risk estimates for gravidic TTP associated with demographic and clinical variables
From: Pregnancy complications in acquired thrombotic thrombocytopenic purpura: a case–control study
Gravidic TTP (n = 4) | Uncomplicated pregnancy (n = 6) | OR (95% CI) | |
|---|---|---|---|
Age ≤ 30 years | 3 | 2 | 6.0 (0.4 – 101.6) |
Age >30 years | 1 | 4 | ref |
Primigravidae | 2 | 5 | 0.2 (0.01 – 3.7) |
Multigravidae | 2 | 1 | ref |
Non-recurrent TTP | 3 | 2 | 6.0 (0.4 – 101.6) |
Recurrent TTP | 1 | 4 | ref |
Time from previous TTP ≤24 months | 1 | 1 | 1.7 (0.08 – 37.7) |
Time from previous TTP >24 months | 3 | 5 | ref |
ADAMTS13 activity <25% in the first trimester* | 2 | 0 | ∞ (2.9 - ∞) |
ADAMTS13 activity ≥25% in the first trimester* | 0 | 5 | ref |
Positive anti-ADAMTS13 antibodies in any trimester | 4 | 0 | ∞ (6.6 - ∞) |
Negative anti-ADAMTS13 antibodies in any trimester | 0 | 6 | ref |