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Table 4 Risk estimates for gravidic TTP associated with demographic and clinical variables

From: Pregnancy complications in acquired thrombotic thrombocytopenic purpura: a case–control study

  Gravidic TTP (n = 4) Uncomplicated pregnancy (n = 6) OR (95% CI)
Age ≤ 30 years 3 2 6.0 (0.4 – 101.6)
Age >30 years 1 4 ref
Primigravidae 2 5 0.2 (0.01 – 3.7)
Multigravidae 2 1 ref
Non-recurrent TTP 3 2 6.0 (0.4 – 101.6)
Recurrent TTP 1 4 ref
Time from previous TTP ≤24 months 1 1 1.7 (0.08 – 37.7)
Time from previous TTP >24 months 3 5 ref
ADAMTS13 activity <25% in the first trimester* 2 0 ∞ (2.9 - ∞)
ADAMTS13 activity ≥25% in the first trimester* 0 5 ref
Positive anti-ADAMTS13 antibodies in any trimester 4 0 ∞ (6.6 - ∞)
Negative anti-ADAMTS13 antibodies in any trimester 0 6 ref
  1. *ADAMTS13 activity levels in the first trimester were available in 2 cases and 5 controls.