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Table 3 Comparison of HRQOL scores between patients with a less severe and more severe movement disorder

From: Rare inborn errors of metabolism with movement disorders: a case study to evaluate the impact upon quality of life and adaptive functioning

Severity of movement disorder Minimal to moderate n = 14 Marked to severe n = 9 U-value Z-value p -value*
Mean value (SD) Mean value (SD)
Total score 59.00 (17.92) 33.67 (19.55) 22.00 -2.60 0.009
Physical functioning 49.64 (22.28) 20.44 (18.08) 18.00 -2.84 0.003
Emotional functioning 69.57 (20.33) 54.44 (26.75) 40.00 -1.45 0.159
Social functioning 59.86 (26.24) 31.67 (27.04) 48.00 -2.21 0.028
School functioning 57.36 (29.27) 39.22 (35.52) 45.50 -1.11 0.277
  1. HRQOL scores were measured on the PedsQL 4.0 Generic Core Scales. The total cohort was divided in two groups based on the severity of their movement disorder, determined by the expert panel.
  2. HRQOL Health-related quality of life, SD Standard deviation; *significance level after Bonferroni-Holm correction for multiple comparisons.
  3. Bold text: statistically significant.