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Table 2 Induction of amenorrhea

From: Management of endocrino-metabolic dysfunctions after allogeneic hematopoietic stem cell transplantation

1. GnRH agonist (3.75 mg/month subcutaneous leuprolide acetate, in general), enabling
a. induction of amenorrhea
b. “parenteral” contraceptive effect effective even in patients with vomiting
c. possible anti-apoptotic, protective effect on the follicles, observed in animal studies but not yet in women.
2. In order to avoid flare-ups, it is recommended to prescribe
a. a contraceptive pill 10 to 15 days after the agonist injection
b. or a macroprogestin for the first month.