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Table 1 Uptake and budget impact of orphan drugs in the Netherlands

From: Orphan drugs expenditure in the Netherlands in the period 2006–2012

  2006 2007 2008 2009 2010 2011 2012
Number of orphan drugs
Outpatient 9 15 18 22 25 30 32
Inpatient 2 7 8 9 11 11 11*
Total 11 22 26 31 36 41 43
Number of patients treated with orphan drugs
Outpatient 2,149 3,457 4,410 6,024 7,621 8,250 9,226
Inpatient 40 146 215 469 531 536 536*
Total 2,189 3,603 4,625 6,493 8,152 8,786 9,762
Budget impact of orphan drugs (millions)
Outpatient €52.7 €68.7 €97.8 €118.1 €141.6 €156.2 €175.2
Inpatient €8.5 €29.2 €60.7 €74.6 €84.3 €85.1 €85.1*
Total €61.2 €97.9 €158.6 €192.7 €225.9 €241.4 €260.4
  1. *For inpatient drugs, figures for 2012 were assumed equal to 2011.