Figure 3

City size versus D-prevalence in large cities in Ontario, Canada. In order to eliminate overestimation biases due to large families with HHT living in small cities, the D-prevalence of HHT was compared in large cities, defined as those centers with a population ≥50,000. Even amongst these cities, there was still significant variation in the D-prevalence across regions, which ranged from no cases to 1.1 cases per 5000 adults. There was no correlation between the population size and the D-prevalence (R² = 0.0005).