Skip to main content
Figure 2 | Orphanet Journal of Rare Diseases

Figure 2

From: Expression of the SERPING1 gene is not regulated by promoter hypermethylation in peripheral blood mononuclear cells from patients with hereditary angioedema due to C1-inhibitor deficiency

Figure 2

Bisulphite sequencing. Chromatograms showing the results of bisulphite sequencing in: (A) Huh7 hepatoma cells in CpG islands 1 and 2 (left and right panels, respectively), (B) Sequence of the bisulphite-modified CpG island 1 in type I and type II HAE patients (left and right panels, respectively) and (C) CpG island 2 type I and type II HAE patients (left and right panels, respectively) (C). Arrows indicate the CpG positions susceptible of methylation. Wild Type sequences are: CpG Island 1: tgggctcccagggtgggagCtggctcCGaggctggctggctcCGcaggtcCGctgaCG. CpG Island 2: tggaggcCGaggCGggtggatcaCGaggtcaggagatCGagacccatcctggctaacaCG.

Back to article page

Orphanet Journal of Rare Diseases

ISSN: 1750-1172