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Table 1 Specific genetic renal diseases in the adult CKD population (n = 2935)

From: The prevalence and epidemiology of genetic renal disease amongst adults with chronic kidney disease in Australia

Genetic renal disease Number CKD cohort prevalence General population prevalence (per million population 18 + yrs)* eGFR mean/median (ml/min/m2) Age mean/median (years) Female
Autosomal dominant polycystic kidney disease 127 4.3% 60.88 50.72/46 53.37/53.53 51.18%
Congenital anomalies of the kidney and urinary tract 106 3.6% 50.81 41.74/38 54.52/56.90 48.11%
Medullary cystic kidney disease 15 0.5% 7.19 45.87/39 48.65/49.27 60%
Thin basement membrane nephropathy 12 0.4% 5.75 82.33/91 51.04/57.01 91.67%
Alport syndrome 5 0.2% 2.40 85.4/91 29.46/25.61 80%
Tuberous sclerosis complex 5 0.2% 2.40 64.4/69 56.34/51.63 100%
Atypical hemolytic uremic syndrome 3 0.2% 2.40 45.67/44 36.66/41.44 100%
Birt-Hogg-Dube syndrome 3 0.1% 1.44 69.33/91 55.79/52.75 100%
Membranoproliferative Glomerulonephritis Type 2 (“Dense deposit disease”) 2 0.1% 0.96 48/48 61.25/61.25 50%
Fabry disease 2 0.1% 0.96 88/88 57.77/57.77 50%
Nephronophthisis 2 0.1% 0.96 40.5/40.5 25.46/25.46 50%
Familial focal segmental Glomerulosclerosis 2 0.1% 0.96 65/65 30.50/30.50 50%
Gitelman syndrome 1 0.1% 0.48 91/91 27.89/27.89 100%
Nail Patella syndrome 1 0.1% 0.48 27/27 30.30/30.30 0%
Renal tubular acidosis 1 0.1% 0.48 20/20 81.28/81.28 0%
TOTAL 287 9.8% 137.58 49.72/45 52.6/53.39 54.01%
  1. *Based upon the 2011 Australian bureau of statistics population of 2,086,055 persons aged 18 years or over residing in the areas served by the 5 sites included.