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Figure 3 | Orphanet Journal of Rare Diseases

Figure 3

From: Intractable itch relieved by 4-phenylbutyrate therapy in patients with progressive familial intrahepatic cholestasis type 1

Figure 3

Itching intensity in the patients before, during, and after the course of 4PB therapy. (A, B) Correlation diagram of itching scores for the PFIC1 patients with serum ATX activity (A) and ATX level (B) in the patients before, during, and after 4PB therapy. Pruritus severity was scored ranging from 0 (no pruritus) to 4 (cutaneous mutilation, with bleeding and scarring) as described in Patients and Methods. (C) Skin of the patients before and after the 4PB therapy.

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