Figure 4
From: Pathognomonic oral profile of Enamel Renal Syndrome (ERS) caused by recessive FAM20A mutations
Gingival and dental-follicle ectopic calcifications in patients with ERS. (A) Gingival hyperplasia. (B-C) H&E staining of resected gingiva showing ectopic calcification in connective tissue. Note the lamellar concentric layer surrounding the central core of the calcification. (D) Hyperplastic dental follicle well delimited by a sclerotic margin. (E) H&E staining of resected follicle showing a similar group of ectopic calcification. (F) Magnification of boxed area from E. Scale bar: (E): 200 μm; (C, F): 50 μm.