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Table 1 Multicenter evaluation of triggering potency

From: Functional and genetic characterization of clinical malignant hyperthermia crises: a multi-centre study

Trigger No. of patients Clinical grading scale
    (raw score)
  MHS MHE MHS MHE
Vol. anesthetics 30 6 40.5 (28.5 - 61.0) 34.0 (30.8 - 41.0)
SCh 1 1 15 25
Vol. anesthetics + SCh 134 28 43.0 (30.0 - 55.0) 33.0 (15.0 - 40.0)
Total 165 35 43.0 (30.0 - 55.8) 33.0 (19.0 - 40.0)
  1. The vast majority of the cases were triggered by the combination of volatile anesthetics and succinylcholine (SCh). Remarkable only one MHS case was triggered by SCh alone, along with one MHE case. The clinical grading scale according to Larach et al. 1994 classifies a raw score of more than 35 as very likely to be clinical MH. Data are shown as median and interquartile range (25% - 75%).