Table 3 Concentration of resveratrol and its metabolites in fibroblasts
Cellular concentration (nmoles/mg of proteins) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Control | Patient 1 | Patient 3 | |||||||
Species EFFLUX (hrs) | 0 | 6 | 48 | 0 | 6 | 48 | 0 | 6 | 48 |
Resveratrol | 14.96 ± 2.12 | 1.30 ± 0.21 | 0.83 ± 0.06 | 22.06 ± 1.95 | 1.29 ± 0.11 | 0.74 ± 0.06 | 20.58 ± 1.40 | 1.30 ± 0.17 | 0.89 ± 0.15 |
Resveratrol-3-0-sulfate | 0.15 ± 0.04 | 0.18 ± 0.02 | 0.35 ± 0.03 | 0.18 ± 0.05 | 0.18 ± 0.02 | 0.27 ± 0.02 | 0.08 ± 0.01 | 0.10 ± 0.01 | 0.17 ± 0.02 |
Resveratrol-3-0-glucuronide | nd. | nd. | nd. | nd. | nd. | nd. | nd. | nd. | nd. |
Resveratrol-4′-0-glucuronide | nd. | nd. | nd. | nd. | nd. | nd. | nd. | nd. | nd. |