Figure 6
qPCR result for markers involved in TGFβ signalling pathway (TGFβ-1, TGFβ-2, TGFβ-3, SMAD2, SMAD3 and CTGF). While relative expression of TGFβ-1 and −3 are normal, upregulation of TGFβ-2 and CTGF can be seen in human PXE fibroblasts compared to control cells. (n = 8 and 5 for patients and controls respectively). *p < 0.05.