Figure 5From: Visualization of cholesterol deposits in lysosomes of Niemann-Pick type C fibroblasts using recombinant perfringolysin OQuantitation of colocalization of GST-PFO-positive structures and other cellular components in NPC fibroblasts. (A) Pearson’s correlation coefficient, (B) overlap coefficient for co-immunostaining with GST-PFO and filipin or antibodies against LAMP1, LBPA, golgin-84, PDI, PMP70 or phalloidin used as an actin filament marker. TX, Triton X-100, DiT, digitonin. Data shown are mean ± SEM.Back to article page