Table 4 Mean yearly numbers and costs of diagnostic and therapeutic procedures* in the AMC by disease state
From: Cost-effectiveness of enzyme replacement therapy for type 1 Gaucher disease
Disease state** | Mean costs per procedure in € | Number of procedures | 95% LCL | 95% UCL | Costs in € | 95% LCL | 95% UCL |
|---|---|---|---|---|---|---|---|
Asymptomatic (N = 4) | 20.9 | 70.2 | 25.0 | 102.4 | 1,470 | 455 | 2,152 |
Signs/symptoms (N = 25) | 33.5 | 86.1 | 63.5 | 110.5 | 2,887 | 1,974 | 3,885 |
Recovery (N = 20) | 32.4 | 94.3 | 79.6 | 110.1 | 3,055 | 1,708 | 4,858 |
Splenectomy (N = 5) | 35.4 | 136.6 | 106.8 | 171.1 | 4,836 | 2,544 | 7,145 |
Bone complication (N = 8 | 40.9 | 106.0 | 73.9 | 154.9 | 4,337 | 1,590 | 9,313 |
Multiple complications (N = 22) | 24.0 | 91.3 | 75.2 | 109.8 | 2,194 | 1,652 | 2,826 |
Malignancy (N = 4) | 76.4 | 360.1 | 68.0 | 646.3 | 27,523 | 4,786 | 51,722 |