Bone and lipid phenotypes in the ext2-/-fish are partially rescued by inhibition of PPAR or activation of hedgehog signalling. A, Oil red O (ORO) stain for lipids in fish at 6dpf; B, Alizarin red stain for bones in fish at 6dpf. GW9662 (GW) and purmorphamine (PM) were added into fish water by 60hpf and fish were raised to 6dpf. Minimum 10 fish were scored from each group and experiment was repeated with similar results at least three times. Error bars represent means with SEM.