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Figure 2 | Orphanet Journal of Rare Diseases

Figure 2

From: Stüve-Wiedemann syndrome: LIFR and associated cytokines in clinical course and etiology

Figure 2

The LIFR protein with domains and exons shown. The numbers indicate the location of the 19 exons (figure not to scale). The domains (CRH1, Ig, CRH2, FNIII, TD and CD) are illustrated within their corresponding region of the protein (extracellular, transmembrane, or cytoplasmic). SP: signal peptide; CRH: cytokine receptor homology domain; Ig: Ig-like domain; FNIII: type III fibronectin domain; TM: transmembrane domain; CD: cytoplasmic domain.

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