Figure 2

Oro-lingual and gestural scores in 21 ARX mutated patients compared to 21 age-matched DS patients: 4 ARX patients (red lines) showed the most severe forms, with global scores below 1 for gestural and oro-lingual praxis; 15 ARX patients (blue, green and pink lines) had global scores between 1 and 2.5 with respect to oro-lingual and/or gestural praxis; 3 (green) had a predominantly gestural praxis impairment (difference between the two scores of more than 1), and 2 (pink) had a predominantly oro-lingual praxis impairment; the remaining 2 patients (dark blue) exhibited milder forms with scores just above 3.