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Table 4 Relative risk of cancer in Peutz-Jeghers syndrome

From: Hamartomatous polyposis syndromes: A review

  Resta et al.[41] Giardiello et al.[42]
Study design Retrospective cohort study Meta-analysis
Any cancer 15.1 (CI 10.5-21.2) 15.2
Breast 12.5 (CI 5.1-26.0) 15.2
Cervix 55.6 (CI 17.7-134.0) 1.5
Gynaecological cancers 27.7 (CI 11.3-57.6) NA
Colorectal cancer 13.5 (CI 4.3-32-5) 84.0 (Colon)
Pancreas 139.7 (CI 61.1-276.4) 132
Gastrointestinal cancer 126.2 (CI 73.3-203.4) NA
Ovary NA 27.0
Uterus NA 16.0
Testes NA 4.5
Lung NA 17.0
Small intestines NA 520.0
Stomach NA 213.0
Oesophagus NA 57.0