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Table 4 Relative risk of cancer in Peutz-Jeghers syndrome

From: Hamartomatous polyposis syndromes: A review

 

Resta et al.[41]

Giardiello et al.[42]

Study design

Retrospective cohort study

Meta-analysis

Any cancer

15.1 (CI 10.5-21.2)

15.2

Breast

12.5 (CI 5.1-26.0)

15.2

Cervix

55.6 (CI 17.7-134.0)

1.5

Gynaecological cancers

27.7 (CI 11.3-57.6)

NA

Colorectal cancer

13.5 (CI 4.3-32-5)

84.0 (Colon)

Pancreas

139.7 (CI 61.1-276.4)

132

Gastrointestinal cancer

126.2 (CI 73.3-203.4)

NA

Ovary

NA

27.0

Uterus

NA

16.0

Testes

NA

4.5

Lung

NA

17.0

Small intestines

NA

520.0

Stomach

NA

213.0

Oesophagus

NA

57.0