Table 2 Urine GAG* excretion
Comparator 0.5 mg/kg/week (N = 11 ) | Idursulfase beta 0.5 mg/kg/week (N = 10) | Idursulfase beta 1.0 mg/kg/week (N = 10 ) | |
|---|---|---|---|
Baseline | 129.1(±59.9) | 164(±53.1) | 124.7(±36.1) |
4 weeks | 105.6(±56) | 112.3(±56.7) | 73.5(±35.7) |
8 weeks | 109.8(±67.8) | 103.4(±56.4) | 67.1(±21.7) |
12 weeks | 102.5(±55) | 110.9(±44.1) | 71.9(±24.4) |
16 weeks | 111.1(±69.7) | 107(±46.2) | 63(±24.6) |
20 weeks | 104.6(±62.6) | 111.6(±46.5) | 70.7(±24.5) |
24 weeks | 105.3(±59.6) | 114.4(±45) | 74.5(±27.3) |