Figure 4
From: Pathways systematically associated to Hirschsprung’s disease
Significant sub-network of 53 genes, allowing for one intermediate gene, associated to HSCR (p-value = 0.027) in the Nsp chip. The network analysis [28] is carried out by using the functional analysis options (Set enrichment analysis/NetworkMiner) of Babelomics [26] on the list of genes ranked by the p-values obtained upon the application of a conventional TDT association test as implemented in PLINK [24].