Table 3 Cytokines identified in BALF of NEHI, FB, CF and disease controls: all values expressed as pg/mL
Median | NEHI | FB | CF | Non-CF DC | KW |
|---|---|---|---|---|---|
(IQR) | (N = 22) | (N = 6) | (N = 7) | (N = 6) | p value |
IL-1β1 | 2.1 (0.7, 2.5) | 7.0 (2.5, 10.1) | 27.7 (4.7, 85.9) | 2.7 (2.5, 7.2) | <0.01 |
IL-1ra1 | 449.8 (306.6, 663.2) | 1558.9 (885.9, 1843.1) | 511.8 (308.7, 1567.1) | 369.3 (278.6, 1107.4) | 0.10 |
IL-61 | 2.0 (1.0, 4.7) | 9.7 (3.3, 16.5) | 9.2 (4.6, 10.6) | 2.8 (2.0, 8.4) | 0.04 |
IL-81 | 35.5 (14.5, 71.7) | 171.3 (20.4, 477.7) | 705.2 (521.1, 1504.2) | 120.0 (42.3, 306.6) | <0.01 |
G CSF | 13.2 (6.1, 27.9) | 33.5 (21.8, 48.6) | 13.1 (7.9, 39.4) | 8.0 (5.4, 34.5) | 0.39 |
GM CSF | 4.0 (1.8, 6.0) | 4.0 (1.0, 6.0) | 6.0 (4.0, 6.0) | 1.1 (1.0, 6.0) | 0.59 |
MCP 11 | 27.6 (19.6, 49.6) | 56.1 (51.9, 113.2) | 138.2 (43.9, 335.8) | 21.1 (11.6, 84.8) | 0.01 |
MIP 1β1 | 7.7 (4.4, 20.0) | 22.8 (15.4, 55.3) | 83.3 (36.0, 100.2) | 31.9 (20.0, 140.3) | <0.01 |
TNF α | 0.8 (0.6, 2.0) | 1.7 (1.0, 2.0) | 2.0 (2.0, 4.1) | 1.4 (0.6, 2.7) | 0.06 |
VEGF | 182.1 (89.3, 317.5) | 270.5 (254.7, 486.6) | 149.2 (64.2, 206.4) | 79.6 (42.3, 159.4) | 0.30 |