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Figure 1 | Orphanet Journal of Rare Diseases

Figure 1

From: Niemann-Pick type C1 patient-specific induced pluripotent stem cells display disease specific hallmarks

Figure 1

Colonies of fibroblast-derived human iPSCs. Images of hiPSC colonies cultured on mouse feeder cells (A,B) or matrigel (C,D). The colonies could be easily distinguished by their morphology, showing a high nuclear to cytoplasm ratio and sharp borders, resembling the morphology of human embryonic stem cells (scale bars = 100 μm). The hiPSCs-derived from fibroblasts of a NPC1-patient (E) and unaffected individual (F) displayed a normal karyotype. Karyotyping was performed by Giemsa Trypsin banding.

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172