Table 3 Comparison of study data with prevalence in median age group according to current data from Germany

Sex (m:f)

117:142; 55% female

prevalence for PG: 0.3-1.0/100.000

(Germany: 1000:1040; 51% female)

Age (mean)

21-94 years (57.3 years)

(Germany, 2010: 44.3 years)

Associated inflammatory disorders

Arthrosis, non rheumatoid arthritis

17 (6.6%)

female (45–65 years): 33%

male: (45–65 years): 25%

Rheumatoid arthritis

24 (9.3%)

female (45–64 years): 8.6%

male (45–64 years): 5%

overall: 0.5-0.8%

Chronic inflammatory bowel disease

Overall: 24 (9.3%)

Crohn’s disease:

Crohn’s disease:

120-200/100.000

7 (2.7%)

Ulcerative colitis:

Ulcerative colitis: 17 (6.6%)

160-250/100.000

Endocrine disorders

Thyroid disease

29 (11.2%)

overall: 5.5%

female: 8.9%

male: 1.8%

Diabetes mellitus

66 (25.5%)

international overall (20–79 years): 12%

German overall: 8.9%

Neoplasia

32 (12.4%)

overall: 5-yr.-prevalence: 1.6%

10-yr.-prevalence: 2.4%

Solid neoplasms (overall)

22 (8.5%)

Breast cancer

6 (2.3%)

female (50–59 years): 1-year-prevalence: 0.2%

Lung cancer

3 (1.6%)

female: 50–59 years: 1-year-prevalence: 0.04%

male: 50–59 years: 1-year-prevalence: 0.07%

Prostate cancer

3 (1.6%)

male overall: 1-year-prevalence: 0.1%

male (60–69 years): 1-year- prevalence: 0.5%

Melanoma

3 (1.6%)

female (50–59 years): 1-year.-prevalence: 0.03%

male (50–59 years): 1-year life-prevalence: 0.02%

Hepatocellular carcinoma

2 (0.8%)

overall: 7-8/100.000

Ovarian cancer

2 (0.8%)

female (50–59 years): 1-year life-prevalence: 0.03%

Colon cancer

1 (0.4%)

female (50–59 years): 1-year.-prevalence: 0.1%

male (50–59 years): 1-year-prevalence:

Laryngeal cancer

1 (0.4%)

female: 1-year-prevalence: <0.01%

male: 1-year-prevalence: <0.1%

Glioblastoma multiforme

1 (0.4%)

n.a.

Hematologic/hematopoetic neoplasia

Leukemia, female:1-year-prevalence: 0.01%

AML

1 (0.4%)

CML

2 (0.8%)

Leukemia, male:

Other

7 (2.8%)

1-year-prevalence: 0.01%