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Table 4 Baseline and 24 months laboratory tests for renal function and lipids

From: Assessing the effectiveness of rapamycin on angiomyolipoma in tuberous sclerosis: a two years trial

Patients baseline creatinine 24 month creatinine baseline proteinuria1 24 month proteinuria1 baseline cholesterol/ 24 month cholesterol/ baseline triglycerides 24 month triglycerides
  (mg/dL)/MDRD (ml/min/1.73m2) (mg/dL)/ MDRD (ml/min/1.73m2) (mg/mmol) (mg/mmol) HDL/LDL HDL/LDL (mmol/L) (mmol/L)
      (mmol/L) (mmol/L)   
1 0.84 /76 0.78/81 6.1 12.1 159/89/90 184/74/101 45 52
2 0.93/>90 0.95/>90 22.4 40.0 5 118/46/72 167/54/100 43 63
3 1.22/74   22.5 2 205/74/131   86  
4 0.96/71   10.3 3 176/83/94 3 144 3
5 0.99/87 0.97/88 9.1 8.2 202/63/139 181/44/125 4 116 64
6 0.67/>90 0.58/>90 5.0 9.6 240/86/156 152/63/89 4 198 116
7 1.15/50 0 0.98/60 9.4 28.6 5 192/78/114 188/77/102 47 47
8 1.07/83 1.09/80 5.6 4.0 154/56/98 202/66/120 62 77
9 0.77/>90 0.86/>90 13.2 47.0 5 125/36/90 226/52/136 4 102 186
10 0.85/78 0.77/87 5.0 4.3 212/55/157 167/75/82 4 48 51
11 0.71/>90 0 0.86/78 7.7 9.4 94/40/54 118/41/64 76 62
12 0.42/> 90 0.48/>90 13.3 11.1 142/38/104 193/42/127 117 120
13 0.62/>90 0.61/>90 6.6 9.8 183/96/87 163/84/90 53 41
14 0.83/>90 1.01/>90 6.4 8.9 203/83/120 176/39/104 4 175 163
15 0.68/>90 0.69/>90 9.0 18.2 200/78/122 170/75/80 66 73
16 0.62/>90 0.54/>90 12.9 11.9 156/51/105 120/49/50 4 145 104
17 1.30/42 0 1.24/44 22.4 32.3 5 292/106/189 216/69/147 4 243 117
  1. 0-Patients 7, 11, 17 had undergone a nephrectomy at least one year before the start of the trial.
  2. 1-Expressed as a protein-to-creatinine ratio.
  3. 2-Patient 3 was withdrawn at 12 months of treatment due to nephrotic-range proteinuria that reverted after discontinuation of treatment.
  4. 3-Patient 4 was excluded at 10 months due to acute pyelonephritis and did not want to be rechallenged.
  5. 4-Statins were prescribed in patients 5, 6, 9, 10, 14, 16, 17.
  6. 5- ACEI were prescribed for microalbuminuria in patients 2, 7, 9, 17.