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Table 3 Results of main multicenter and single-center studies of HDM/SCT in AL amyloidosis

From: AL Amyloidosis

Authors (references) Year of publication and N° of patients Clonal response% (PR + CR) CR% TRM% Median survival (years)
Single center studies
Skinner et al. [54] 2004/312 NA 40 ** 13 4,6 **
Sanchorawala et al. [55] 2007/80 NA 37 ** 18 4,75 **
Schonland et al. [56] 2010/58 74 * 46 * 17 > 8 *
Cibeira et al. [57] 2011/421 NA 34 ** 11,4 6,3 **
Madan et al. [58] 2012/187 66 ** 30 ** 15 4,5 **
Multicenter studies
Vesole et al. [59] 2003/107 32 ** 16 ** 27 3,9 **
Goodman et al. [60] 2006/92 66 ** 35 ** 23 5,3 **
Jaccard et al. [21] 2007/50 36 * 22 * 26 1,8 *
  1. * Intent to treat after inclusion in an intensive treatment program **only after intensive treatment.