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Table 3 Characteristics of pemphigus-related substrates used in the BIOCHIP mosaic

From: Serological diagnosis of autoimmune bullous skin diseases: Prospective comparison of the BIOCHIP mosaic-based indirect immunofluorescence technique with the conventional multi-step single test strategy

Disease Desmoglein 1 Desmoglein 3
Pemphigus vulgaris 33/65 64/65
 Sensitivity 52.3 98.5
 95%CI 39.5% to 64.9% 91.7% to 100%
 Specificity 100 99.6%
 95%CI 98.6% to 100% 98.6% to 100%
Pemphigus foliaceus 45/50 3/50
 Sensitivity % 90% not applicable
 95%CI 78.2% to 96.7%  
 Specificity % 100% 99.6%
 95%CI 98.6% to 100% 97.9% to 100%
Linear IgA disease 0/18 0/18
Bullous pemphigoid 0/42 1/42
HBD 0/100 0/100
NISD 0/97 0/97
  1. HBD, healthy blood donors; NISD, non-inflammatory skin diseases; 95%CI, 95% confidence intervals.