Skip to main content

Table 3 Characteristics of pemphigus-related substrates used in the BIOCHIP mosaic

From: Serological diagnosis of autoimmune bullous skin diseases: Prospective comparison of the BIOCHIP mosaic-based indirect immunofluorescence technique with the conventional multi-step single test strategy

Disease

Desmoglein 1

Desmoglein 3

Pemphigus vulgaris

33/65

64/65

 Sensitivity

52.3

98.5

 95%CI

39.5% to 64.9%

91.7% to 100%

 Specificity

100

99.6%

 95%CI

98.6% to 100%

98.6% to 100%

Pemphigus foliaceus

45/50

3/50

 Sensitivity %

90%

not applicable

 95%CI

78.2% to 96.7%

 

 Specificity %

100%

99.6%

 95%CI

98.6% to 100%

97.9% to 100%

Linear IgA disease

0/18

0/18

Bullous pemphigoid

0/42

1/42

HBD

0/100

0/100

NISD

0/97

0/97

  1. HBD, healthy blood donors; NISD, non-inflammatory skin diseases; 95%CI, 95% confidence intervals.