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Table 1 Classification of most frequent causes of Cushing’s syndrome

From: Cushing’s disease

ACTH dependent
Cushing’s syndrome
Cushing’s disease or ACTH secreting
pituitary adenoma
  Ectopic ACTH secretion
ACTH independent
Cushing’s syndrome
Adrenal adenoma
  Adrenal carcinoma
  Bilateral adrenal hyperplasia
  Iatrogenic Cushing’s syndrome
(Exogenous glucocorticoid exposure)
Pseudo-Cushing’s
syndrome
Obesity
  Alcoholism
  Depression
  1. Modified from Williams Textbook, 12th Edition