Figure 1From: 3-methylcrotonyl-CoA carboxylase deficiency: Clinical, biochemical, enzymatic and molecular studies in 88 individualsClinical manifestation of 33 symptomatic individuals with MCC deficiency. One patient who died of sudden cardiac arrest at the age of 8 years was excluded from this figure as catecholaminergic ventricular tachycardia with mutations in the RyR2 gene was identified as a likely cause for the cardiac symptoms.Back to article page