Table 1 Characteristics of adults with at least two subcutaneous neurofibromas (cases) and controls
From: At-Risk Phenotype of Neurofibromatose-1 Patients: A Multicentre Case-Control Study
Clinical features | Cases n = 106 | Controls n = 102 | p value* |
|---|---|---|---|
Matching variables | |||
Female gender | 62 (59) | 62 (61) | |
Age (years) | 41 (± 13) | 41 (± 14) | |
Clinical variables | |||
Familial case | 56 (47) | 56 (45) | 0.76 |
No cutaneous neurofibromas | 13 (12) | 4 (4) | 0.03 |
Plexiform neurofibromas | 66 (62) | 49 (48) | 0.04 |
Large café-au-lait spots (number) | 8.6 (± 4.8) | 10.1 (± 10.1) | 0.07 |
No freckles | 21 (20) | 12 (12) | 0.11 |
Lisch nodules | 48 (81) | 45 (80) | 0.89 |
Scoliosis | 46 (43) | 42 (41) | 0.75 |
Headache | 38 (36) | 41 (40) | 0.52 |
Epilepsy | 2 (2) | 2 (2) | 0.97 |
Learning disabilities | 58 (57) | 52 (49) | 0.26 |