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Table 1 Summary of patient characteristics

From: Population pharmacokinetics and pharmacodynamics of hydroxyurea in sickle cell anemia patients, a basis for optimizing the dosing regimen

 

PKPD dataset

Rich PK dataset

Characteristics

Median (range)

Median (range)

Age

30 (18 - 54)

32 (24 - 52)

Men/women

24/57

5/11

Weight (kg)

60 (45 - 163)

63 (42 - 71)

Creatinine (μM)

65 (27 - 558)

72 (47 - 129)

Urea (μM)

3.1 (0.8 - 10.5)

3.4 (2.4 - 7.7)

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172