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Table 1 Summary of patient characteristics

From: Population pharmacokinetics and pharmacodynamics of hydroxyurea in sickle cell anemia patients, a basis for optimizing the dosing regimen

  PKPD dataset Rich PK dataset
Characteristics Median (range) Median (range)
Age 30 (18 - 54) 32 (24 - 52)
Men/women 24/57 5/11
Weight (kg) 60 (45 - 163) 63 (42 - 71)
Creatinine (μM) 65 (27 - 558) 72 (47 - 129)
Urea (μM) 3.1 (0.8 - 10.5) 3.4 (2.4 - 7.7)