Table 6 Associations between periconceptional exposures to body weight
From: Parental risk factors and anorectal malformations: systematic review and meta-analysis
| Maternal overweight/obesity | ||||
|---|---|---|---|---|
| Ref. | First author, year | Exposure | OR [95% CI] | Adjustment/matching factors |
| [26] | Blomberg, 2010 |
BMI < 18.5 BMI 18.5 - 24.9 BMI 25 - 29.9 BMI ≥30 |
1.22 [0.63, 2.13] 1.00 Reference 1.21 [0.98, 1.51] 1.87 [1.42, 2.47] |
Adjusted for: maternal age, parity, smoking in early pregnancy and year of birth using the Mantel-Haenszel method |
|
BMI 30 - 34.9 BMI 35 - 39.9 BMI ≥40 |
1.77 [1.29, 2.44] 1.48 [0.74, 2.64] 3.72 [1.70, 7.07] | Adjusted for: see above | ||
| [39] | van Rooij, 2010** |
BMI 25 - 29.9 BMI ≥30 |
1.8 [1.1, 3.0] 1.4 [0.6, 3.2] | N/A* |
| [40] | Waller, 2007 |
BMI < 18.5 BMI 25 - 29.9 BMI ≥30 |
0.81 [0.48, 1.36] 1.19 [0.92, 1.55] 1.46 [1.10, 1.95] |
Adjusted for: maternal age, ethnicity, education, parity, smoking in the month prior to conception and supplemental folic acid intake in the month prior to conception |