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Table 6 Associations between periconceptional exposures to body weight

From: Parental risk factors and anorectal malformations: systematic review and meta-analysis

   Maternal overweight/obesity   
Ref.    First author, year Exposure OR [95% CI] Adjustment/matching factors
[26]    Blomberg, 2010 BMI < 18.5
BMI 18.5 - 24.9
BMI 25 - 29.9
BMI ≥30
1.22 [0.63, 2.13]
1.00 Reference
1.21 [0.98, 1.51]
1.87 [1.42, 2.47]
Adjusted for: maternal age, parity, smoking in early pregnancy and year of birth using the Mantel-Haenszel
method
   BMI 30 - 34.9
BMI 35 - 39.9
BMI ≥40
1.77 [1.29, 2.44]
1.48 [0.74, 2.64]
3.72 [1.70, 7.07]
Adjusted for: see above
[39]    van Rooij, 2010** BMI 25 - 29.9
BMI ≥30
1.8 [1.1, 3.0]
1.4 [0.6, 3.2]
N/A*
[40]    Waller, 2007 BMI < 18.5
BMI 25 - 29.9
BMI ≥30
0.81 [0.48, 1.36]
1.19 [0.92, 1.55]
1.46 [1.10, 1.95]
Adjusted for: maternal age, ethnicity, education, parity,
smoking in the month prior to conception and supplemental
folic acid intake in the month prior to conception
  1. * The association was not confounded by any covariable.
  2. ** More detailed information on the results was obtained directly through the author.