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Table 6 Associations between periconceptional exposures to body weight

From: Parental risk factors and anorectal malformations: systematic review and meta-analysis

  

Maternal overweight/obesity

  

Ref.

   First author, year

Exposure

OR [95% CI]

Adjustment/matching factors

[26]

   Blomberg, 2010

BMI < 18.5

BMI 18.5 - 24.9

BMI 25 - 29.9

BMI ≥30

1.22 [0.63, 2.13]

1.00 Reference

1.21 [0.98, 1.51]

1.87 [1.42, 2.47]

Adjusted for: maternal age, parity, smoking in early pregnancy and year of birth using the Mantel-Haenszel

method

  

BMI 30 - 34.9

BMI 35 - 39.9

BMI ≥40

1.77 [1.29, 2.44]

1.48 [0.74, 2.64]

3.72 [1.70, 7.07]

Adjusted for: see above

[39]

   van Rooij, 2010**

BMI 25 - 29.9

BMI ≥30

1.8 [1.1, 3.0]

1.4 [0.6, 3.2]

N/A*

[40]

   Waller, 2007

BMI < 18.5

BMI 25 - 29.9

BMI ≥30

0.81 [0.48, 1.36]

1.19 [0.92, 1.55]

1.46 [1.10, 1.95]

Adjusted for: maternal age, ethnicity, education, parity,

smoking in the month prior to conception and supplemental

folic acid intake in the month prior to conception

  1. * The association was not confounded by any covariable.
  2. ** More detailed information on the results was obtained directly through the author.