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Table 2 Comparison between Drosophila and humans regarding the compensation-dose mechanism (based on Dobyns et al., 2004 [48])

From: Expression of the disease on female carriers of X-linked lysosomal disorders: a brief review

Characteristics

Drosophila

Human

Female

6A+XX

46, XX

Male

6A+XY

46, XY

Fertile

6A+XX and 6A+XY

46, XX and XY

Infertile

6A+XO

45, X

Dosage compensation in X chromosome

Transcribing rate of the X chromosome

X-inactivation

X- inactivation

No

Yes