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Table 6 Differential diagnosis of inherited EB (in neonates and small children) *

From: Inherited epidermolysis bullosa

Inherited or congenital disorders  
  Epidermolytic hyperkeratosis (bullous congenital ichthyosiform erythroderma)
  Ichthyosis bullosa of Siemens
  Peeling skin syndrome
  Pachyonychia congenita
  Congenital porphyrias
  Acrodermatitis enteropathica
  Incontinentia pigmentii
  Ectodermal dysplasia (ED)
     AEC syndrome (Hay-Wells syndrome)
  Congenital absence of skin (cutis aplasia)
  Congenital erosive dermatosis with reticulate supple scarring
Acquired disorders  
  Immunobullous disorders
     EB acquisita
     Linear IgA dermatosis
     Bullous pemphigoid
     Cicatricial pemphigoid
     Neonatal herpes gestationis
     Pemphigus
  Infectious diseases
     Herpes simplex
     Staphylococcal scalded skin syndrome
     Bullous impetigo
  Other diseases or conditions
     Bullous mastocytosis
     Traumatic blisters (sucking; other)
  1. * modified from Fine JD et al, 2000 [5]