Table 2 Clinical characteristics of Neurofibromatosis type 2 patients in four studies
From: Neurofibromatosis type 2 (NF2): A clinical and molecular review
Characteristic | Study | Â | Â | Â |
|---|---|---|---|---|
| Â | Kanter et al. [11] | Evans et al. [1] | Parry et al. [12] | Mautner et al. [13] |
Number of cases | 73 | 120 | 63 | 48 |
Number of families | 17 | 75 | 32 | 44 |
Sporadic cases | 0 | 45 | 17 | 44 |
Mean age at onset (years) | 20 (of 59) | 22 | 20 | 17 |
Intracranial meningiomas (%) | 18 | 45 | 49 | 58 |
Spinal tumours (%) | NA | 26 | 67 | 90 |
Skin tumours (%) | 32 (of 73) | 68 (of 100) | 67 | 64 |
Café-au-lait macules (%) | 42 (of 31) | 43 (of 100) | 47 | NA |
Cataract (%) | NA | 38 (of 90) | 81 | 62 |
Intracranial astrocytoma (%) | NA | 4.1 | 1.6 | NA |
Ependymoma (%) | NA | 2.5 | 3.2 | 6 |
Optic sheath meningioma (%)1 | NA | 4.1 | 4.8 | 8 |