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Table 1 Summary of simulation results for the designs

From: Adaptive design methods in clinical trials – a review

Method Assumed True MTD Mean Predicted MTD Mean Number of Patient Mean Number of DLTs
3+3 TER 100 86.7 14.9 2.8
CRM 100 99.2 13.4 2.8
3+3 TER 150 125 19.4 2.9
CRM 150 141 15.5 2.5
3+3 TER 200 169 22.4 2.8
CRM 200 186 16.8 2.2
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172