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Table 1

From: Successful bone marrow transplantation in a patient with DNA ligase IV deficiency and bone marrow failure

Bleomycin μg/ml

0

0.1

0.25

0.5

negative control

0.06

0.48

0.5

0.98

patient

0.02

1.04

1.28

1.78

positive control

0.06

1.33

1.52

2.4

  1. Chromosome breakage rates (percent breaks per cell) of peripheral blood mononuclear cells exposed to the respective concentrations of the radiomimetic bleomycin for four hours. Negative control = blood samples from healthy donors; positive control = blood sample from a proven AT patient.
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172