Table 1 Extent of organ involvement
Stage | Skin | Liver (bilirubin) | Gut (stool output/day) |
|---|---|---|---|
0 | No GVHD rash | < 2 mg/dl | < 500 ml/day or persistent nausea. |
1 | Maculopapular rash< 25% BSA | 2–3 mg/dl | 500–999 ml/day |
2 | Maculopapular rash 25 – 50% BSA | 3.1–6 mg/dl | 1000–1500 ml/day |
3 | Maculopapular rash > 50% BSA | 6.1–15 mg/dl | Adult: >1500 ml/day |
4 | Generalized erythroderma plus bullous formation | >15 mg/dl | Severe abdominal pain with or without ileus |
Grade | |||
I | Stage 1–2 | None | None |
II | Stage 3 or | Stage 1 or | Stage 1 |
III | - | Stage 2–3 or | Stage 2–4 |
IV | Stage 4 or | Stage 4 | - |