Figure 2

Schematic representation of the structure of the GPIIIa (β3) gene (ITGB3) together with a representative spectrum of the types of genetic abnormalities that give rise to Glanzmann thrombasthenia (GT). Note that abnormalities are abundant in both αIIb and β3 genes and that no parts of either gene appear to be exempt. For further information see the legend to Figure 1.