The rare cancers section of the OJRD publishes articles on the epidemiology, aetiology, description, characterization (in terms of molecular and cellular biology), pathology, clinical behavior, and response to treatment of rare cancers. Articles include a multidisciplinary assessment, covering the different aspects of a novel disease entity, from preclinical experiments to translational and clinical research. Descriptions of novel entities, molecular subtypes, etiology, and pioneering work of clinical research of these rare subtypes are welcome.
Synergistic apoptosis following endoplasmic reticulum stress aggravation in mucinous colon cancer
Mucinous colon cancers (MCC) are characterized by abundant production of mucin 2 (MUC2) protein and are less sensitive to standard systemic chemotherapy. We postulated that severe/persistent endoplasmic reticu...