Fig. 3
Diagnostic investigations for WD diagnosis at German university centers subdivided into medical disciplines. Fifty-five departments provided data on the use of diagnostic investigations (20 departments of pediatrics, 14 departments of neurology and 21 departments of gastroenterology). The percentages reported by the participating centers are displayed (median with interquartile range; values are shown in Additional file 1: Material 6). Most departments perform diagnostic investigations as recommended by guidelines, e.g., determination of ceruloplasmin and copper in patients’ sera as well as urinary copper excretion