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Table 1 Main characteristics of the studies included

From: Quality of life of pediatric and adult individuals with osteogenesis imperfecta: a meta-analysis

Author, year (origin)

NG author, year (origin)

Group of comparison

Sample size (n female)

Mean age in years

QoL measure

OI total

OI I

OI III

OI IV

NG/HC

OI

NG/HC

Gooijer et al. [32] (Netherlands)

Aaronson et al. [1] (Netherlands)

OI type I, III, IV and norm group

322 (189)

220 (139)

40 (19)

62 (31)

1742 (766)

36

48

SF-36

Hald et al. [33] (Denmark)

Bjorner et al. [12] (Denmark)

OI type I, III, IV and norm group

84 (46)

58 (33)

11 (4)

15 (9)

4048 (2141)

45

44

SF-36

Murali et al. [67] (United States)

Gandek et al. [30] (United States)

OI type I, III, IV, and norm group

302 (207)

173 (128)

49 (32)

80 (47)

′105 (926)

36

41–48**

SF-12

Orlando et al. [69] (United Kingdom)

Jenkinson et al. [44]* (United Kingdom)

OI type I, III, IV, and norm group

52 (39)

32 (24)

10 (7)

10 (8)

8801 (4′938)

44

40 **

SF-36

Song et al. [87] (China)

Control group within study

OI type I, III, IV and healthy controls

138 (50)

73 (30)

30 (11)

35 (9)

138 (50)

10

11

PedsQL

Vanz et al. [96] (Brazil)

Klatchoian et al. [46]* (Brazil)

OI type I, III, IV, and norm group

51 (22)

26

12

13

240 (124)

11

9

PedsQL

  1. OI Osteogenesis imperfecta, PedsQL Pediatric quality of life inventory, NG Norm group, HC Healthy controls, SF-36 and SF-12 Short form health survey questionnaire, QoL Quality of life
  2. *Studies for which original authors did not originally provide a comparison group for
  3. **Studies for which only the age range was available