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Table 1 18F-FDG PET/CT findings and treatment of patients

From: The value of 18F-FDG PET/CT in the systemic evaluation of patients with Rosai–Dorfman disease: a retrospective study and literature review

Case

Age/gender

Disease condition

Pre-PET treatment

Involved organs/tissues detected by PET/CT

Post-PET treatment

1

56/M

Suspected recurrence

Resection

Paranasal sinus, nasopharynx and lymph node

Thalidomide and glucocorticoid

2

33/M

Undiagnosed

Multiple intracranial lesions and lymph nodes

Resection, lenalidomide and glucocorticoid

3

70/M

Suspected recurrence

Resection

Paranasal sinus, bilateral nasal cavity and laryngeal

Thalidomide

4

28/F

Suspected recurrence

Biopsy, glucocorticoid

Bilateral cervical lymph nodes

Resection

5

35/M

Newly diagnosed

Resection, glucocorticoid

Orbital apex and nasopharyngeal

Lenalidomide and glucocorticoid

6

26/F

Suspected recurrence

Resection

Nasopharyngeal cavity, superior turbinate, subglottic nodule, subcutaneous nodules and lymph nodes

Lenalidomide and glucocorticoid

7

11/M

Newly diagnosed

Biopsy

Pituitary, nasal cavity, nasopharyngeal and multiple bone lesions

Glucocorticoid

8

22/M

Undiagnosed

Throat and lymph node

Resection and thalidomide

9

57/M

Newly diagnosed

Resection

Nasal cavity, subglottic nodule and pituitary

Thalidomide

10

48/F

Undiagnosed

Pulmonary trunk lumen, ascending aortic root wall and lymph nodes

Resection

11

38/M

Newly diagnosed

Biopsy

Subcutaneous nodule

Resection

12

27/F

Newly diagnosed

Resection

Lymph nodes

Observation

13

21/F

Newly diagnosed

Resection

Nasal cavity, paranasal sinus, subcutaneous nodules and lymph nodes

Lenalidomide and glucocorticoid

14

42/M

Newly diagnosed

Resection

Lacrimal gland, parotid gland, nasopharynx, pleura, pericardium, bone, subcutaneous nodules and lymph nodes

Lenalidomide and glucocorticoid

15

37/M

Suspected recurrence

Biopsy, glucocorticoid

Multiple intracranial lesions

Cytarabine

16

32/F

Suspected recurrence

Glucocorticoid

Parotid gland

Lenalidomide and glucocorticoid

17

22/F

Newly diagnosed

Resection

No lesion

Observation

18

51/F

Undiagnosed

Multiple bone lesions and lymph nodes

Lenalidomide and glucocorticoid

19

70/M

Suspected recurrence

Resection, glucocorticoid, radiotherapy, immunosuppressor

Muscles, orbit, paranasal sinus, eyelids, plica vocalis and lymph nodes

Cytarabine

20

33/F

Newly diagnosed

Biopsy

Nasal cavity, trachea, adrenal nodule, subcutaneous nodules and lymph nodes

Glucocorticoid

21

53/M

Newly diagnosed

Biopsy

Multiple bone lesions, subcutaneous nodules and lymph nodes

Lenalidomide and glucocorticoid

22

65/M

Undiagnosed

Multiple intracranial lesions, high-density tissue in T3-4 spinal canal, subcutaneous nodule and lymph nodes

Cytarabine

23

63/F

Newly diagnosed

Resection, glucocorticoid, immunosuppressor

Muscles, bone lesion and subcutaneous nodules

Lenalidomide and glucocorticoid

24

53/M

Suspected recurrence

Resection, glucocorticoid

Extraocular muscles, eyelids, lacrimal glands, parotid gland, laryngeal cavity and perirenal soft tissue

Lenalidomide and glucocorticoid

25

60/M

Undiagnosed

Soft tissue in right atrium

Resection

26

14/M

Suspected recurrence

Biopsy, glucocorticoid, intravenous immunoglobulin

Lymph nodes and bone marrow

Glucocorticoid and methotrexate

27

18/M

Undiagnosed

Multiple intracranial lesions and lymph nodes

Cytarabine

28

39/M

Undiagnosed

Multiple bone lesions and lymph nodes

Lenalidomide and glucocorticoid