Fig. 1

Conventional image characteristics in Gorham–Stout disease. A Plain radiograph images of the left lower leg of a 31-year-old man with Gorham–Stout disease (GSD). A vanishing appearance of left tibial proximal metaphysis and diaphysis (arrowhead) with compensatory hypertrophy of the left fibula is seen (first and second columns). A 7-year follow-up plain radiograph of the left lower leg after surgical correction of deformity showing further progression of the osteolysis (arrowhead) despite the operation (third and fourth columns). B Chest computed tomography (CT) images of a 48-year-old man diagnosed with GSD. On axial non-contrast chest CT images, interlobular septal line thickening and bronchovascular bundle thickening (black arrowheads) were observed in both lungs, with diffuse pleural thickening (white arrowheads) of the bilateral hemithorax. C CT and magnetic resonance images of a 22-year-old man diagnosed with GSD. On axial contrast-enhanced abdominal CT images (first column), multiple small, low-attenuated nodular lesions (arrowhead) were observed in the spleen, but there was no splenomegaly. On axial T2-weighted images (second column), these lesions showed high T2 signal intensities (arrowhead). These could be considered as the splenic manifestation of GSD. Further, there were prominent soft-tissue lesions in the anterior mediastinum and collaterals along the left chest wall (arrows)