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Table 3 Laboratory tests findings in SSc patients with and without myocardial involvement

From: The clinical characteristics and outcomes of patients with systemic sclerosis with myocardial involvement

 

Myocardial involvement (n = 21)

Non- myocardial involvement (n = 63)

P value

Leukopenia

0 (0)

1 (1.6)

1

Thrombocytopenia

2 (9.5)

5 (7.9)

1.000

Elevated IgG

8 (38.1)

22 (34.9)

0.793

Elevated IgA

1 (4.8)

9 (14.3)

0.437

Elevated IgM

1 (9.5)

6 (9.5)

1

Decreased C3

0 (0)/20

7 (11.3)/72

0.186

Decreased C4

1 (5)/20

5 (8.1)/62

1

Elevated ESR

6 (28.6)

23 (37.1)/62

0.479

HsCRP (mg/L)

2.9 (1.4,9.8)

1.5 (0.7,3.7)/61

0.022

Elevated CK

7 (33.3)

3 (4.8)

0.002

ANA positivity

21 (100)

56 (88.9)

0.254

Anti-RNP antibody positivity

4/20 (20)

20 (31.7)

0.313

Anti SCL70 antibody positivity

15 (71.4)

23 (36.3)

0.005

ACA positivity

2/20 (10)

6/59 (10.2)

1

Anti PM-Scl antibody positivity

1/19 (5.3)

1/56 (1.8)

0.445

  1. Ig: immunoglobulin; C3/4: Complement 3/4; ESR: erythrocyte sedimentation rate; hsCRP: High-sensitivity C-reactive protein; CK: creatine kinase; ANA: antinuclear antibody; ACA: anticentromere antibody; RNP: U1-ribonucleoprotein; Anti Scl-70: anti-topoisomerase; PM-Scl: polymyositis-scleroderma