Skip to main content

Table 2 Summary of GT cases with endometriosis

From: Monozygotic twin cases of endometriosis with Glanzmann thrombasthenia: a case report and review of literature

Authors

Year

Type of study

Age

Chief complaint

Medical history

Imaging

Treatment

Surgical findings

Preoperative management

Outcome

Alatas et al. [16]

2009

Case report (two sisters)

28 yrs

Primary infertility

- GT was diagnosed at the age of 3

- Frequent blood transfusion, mainly due to epistaxis

- wedge

resection for polycystic ovary syndrome

-cystectomy for a presumed left ovarian chocolate cyst 2005

Transvaginal ultrasonography demonstrated a 3.5 cm cystic lesion suggestive of endometrioma

Surgical exploration- laparoscopy- cystectomy

- Diffuse adhesions

- superficial endometriotic lesions over the left

ovarian fossa

- a right ovarian cyst

- Four units of apheresis platelet concentrate

- one unit of

whole blood

Discharged after 3 days

24 yrs

Pelvic mass discovered following abdominal pain and distension for 2 years and

- GT was diagnosed at the age of 11 following by gastrointestinal tract bleeding

- History of Hepatitis C

MRI

showed a huge, septated, cystic mass (extending from

the pelvic floor to the upper abdomen)

Surgical exploration- laparotomy- cystectomy and partial omentectomy

- A cystic mass of about 20*15 cm,

firmly attached to the adjacent tissues

- Focal necrotic areas in Omentum surrounding the mass

- the mass composed of two separate cysts

bilaterally originating from ovaries

Not mentioned

Discharged after 5 days

Imperiale et al. [11]

2015

Letter to the editor (three sister, of whom two were twins)

28 yrs

Dysmenorrhea, deep dyspareunia and

severe menometrorrhagia

- GT was diagnosed after severe epistaxis a few days after birth

Transvaginal pelvic ultrasounds demonstrated

a 70-mm hypoechoic and corpuscular cystic mass suggestive of endometrioma and a suspected

intrauterine polyp of 20 mm (left adnexal)

After 11

months of medical follow-up to avoid surgery, transvaginal ultrasound (TVUS)

revealed

a new endometriotic cyst of 34 × 34

mm in left ovary

Surgical exploration- laparoscopy -hysteroscopic

polyp removal

-

- 3 months of gonadotropin-releasing

hormone analogs (GnRH-a) (triptorelin acetate 3.75 mg, intramuscular once a month) prior to surgery

- rFVIIa (~ 90

mcg/kg) before and after surgery

- Tranexamic acid 500 mg during the perioperative

period

Postoperative TVUS showed the presence of a hematometra of

11.7 mm which was resolved and after 30 days patient was discharged

40 yrs

Severe menorrhagia, mild

dysmenorrhea and deep dyspareuni

- GT

- severe heavy menstruation after the menarche

Abdominal and vaginal ultrasonographywas consistant with physical examination that endometriotic nodule of about 50 mm in diameter in

the rectovaginal septum was recognized

Medical treatment and follow-up

-

-

Follow-ups were satisfying

28 yrs

Heavy menstrual bleeding

- GT

Transvaginal

ultrasonography showed a 35 mm cystic lesion

with mixed echogenicity in the right ovary, not vascularized at

Doppler

Medical treatment and follow-up

-

-

Follow-ups were satisfying

Pillai et al. [23]

2019

Case report

35 yrs

Infertility

- GT was diagnosed since childhood following episodes of epistaxis

and heavy menstrual bleeding

Pelvic MRI demonstrated a 6,4 cm left-ovarian cyst, suggestive of endometrioma

Surgical exploration- laparotomy- ovarian cystectomy- intraperitoneal-drain

 

- rFVIIa 90 lg/kg intra-

venously

- One unit of packed red cells

- Three units of platelet transfu-

Sion

-Tranexamic acid every 1 g 6 h

Discharged after 6 days